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PhosChol: Put the body on offense
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PhosChol: A Membrane Therapeutic for Liver Disturbances

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PPC is incorporated into liver cell membranes in toto as shown with the help of double-radioactive labeling. Clinical studies suggest that PPC:

For Use In Acute and Chronic Disorders of the Liver

Every year doctors around the world prescribe polyenylphosphatidylcholine (PPC) to millions of patients with liver disorders. The positive experience doctors and patients have with PPC, the main ingredient in PhosChol, is due to its unique mode of action.

A loss of phospholipids is seen irrespective of the etiology in liver disorders in which there is damage to the hepatocyte membranes and organelles. Exogenous substitution of phospholipids in the form of PPC leads to the incorporation of PPC into the membranous structures of the liver cell and thus to membrane regeneration. The proof of the unique mode of action and thus the therapeutic relevance of PPC was primarily demonstrated by a large number of different pharmacological studies carried out all over the world and now is continually completed on the basis of new scientific methods.

Clinical Studies Confirm

In numerous international clinical studies with more than 10,000 patients, well-known clinicians checked the therapeutic possibilities of PPC in the treatment of liver disorders of different etiology and confirmed the knowledge gained during pharmacological examinations.

References & Areas of Use

References:

  1. Zierenberg, O. and Grundy, S.M., J. Lipid. Res., 23:1136 (1982).
  2. Dargel R. et al., Z. Gastroenteral. 29 (Suppl. 2):18 (1991).
  3. Lekim, D. and Betzing, H., Arzneimit Forsch, 2: 1772 (1976).
  4. Indovina, J. et al., Epatologica, 27:261 (1981).
  5. Navder K. P. and Lieber C. S., Biochem. Biophys. Res. Commun. 291:1109 (2002).
  6. Müting, D. et al., Verh. Dtsch. Ges. innere Med., 78:1389 (1972).
  7. Kuntz, H. D. it al., Med. Welt., 29:452 (1978).
  8. Chanussot, F. and Benaoel, L., Life Sciences 73:381 (2003).
  9. Saratikov A.S. and Vengerovskii A.I., Biull. Eksp. Biol. Med. 127:392 (1999).
  10. Alliet, J. et al., L’Quest Medical, 29:85 (1976).
  11. Holecek, M. et al., in: Liver and Drugs 1994 edt. by J. Holoman and J. Glasa. Progress in Hepato-Pharmacol. 1:202 (1995).

Areas of Use

As adjuvant in acute and chronic hepatitis; cirrhosis; intoxications; fatty degeneration of the liver of any origin; functional cholestasis; prophylaxis of gallstone formation; radiation syndrome; pre-and postoperative care, especially in liver/gallbladder surgery.

Dosage and Administration:

Unless otherwise prescribed by the physician, 2-3 grams (2-3 capsules or 1 tsp. liquid concentrate) once daily. To be administered during meals, with a little liquid if required.